Usefulness of atrial function for risk stratification in asymptomatic severe aortic stenosis
Todaro MC, Carerj S, Khandheria B, et al. Usefulness of atrial function for risk stratification in asymptomatic severe aortic stenosis. J Cardiol. 2016;67(1):71-9.
AIM: We aimed to evaluate the usefulness of left atrial (LA) mechanics and stiffness over global left ventricular (LV) longitudinal strain (GLS) for risk stratification in severe aortic stenosis (AS).
METHODS: From a cohort of 89 prospective asymptomatic patients with severe AS and normal LV ejection fraction, 82 (32 men, mean age 73±10 years) truly asymptomatic patients, scheduled after a negative exercise echocardiogram, were enrolled. Forty age- and gender-matched prospective, asymptomatic subjects served as controls. Predefined end points were the occurrence of symptoms (dyspnea, angina, syncope), and death during follow-up.
RESULTS: At study entry, patients had: impaired LV GLS (p=0.001), reduced LA reservoir (p0.001), lower LA reservoir (p