•  
  •  
 

Publication Date

4-22-2016

Keywords

mycoses, fungi, histoplasmosis, blastomycosis, sporotrichosis, Aspergillus

Abstract

A number of fungal pathogens that may result in a variety of human diseases are found in residential homes and yards. The growth of these microscopic fungi is often favored by particular characteristics of the dwelling and nearby outdoor environment. Evolved virulence factors or increased ability of specific fungi to grow in diverse, and sometimes harsh, microenvironments presented by the domestic environment may promote growth and pathogenesis. Infection may occur by inhalation or direct inoculation and include endemic fungi in addition to opportunistic or emerging species. Systemic or locally aggressive fungal infections are particularly likely and may be life-threatening in those with compromised immune systems. Allergic disease may include sinusitis, pneumonitis and immediate hypersensitivity. Controversial topics include mycotoxins, volatile organic compounds and sick building syndrome. This narrative review describes the usual presentations, domestic environmental sources, prevention techniques and risk of acquiring these diseases in the Midwestern United States.