Konduri SD, Donohoe D, Holmuhamedov A, Jella T, Bobustuc, GC. MGMT inhibition by disulfiram sensitizes ER+ breast cancer cells to temozolomide and cyclophosphamide. Poster presented at: Aurora Scientific Day; May 2 5, 2016; Milwaukee, WI.
Poster presented at: Aurora Scientific Day; May 25, 2016; Milwaukee, WI.
Conclusion: Our findings suggest that DSF as dual inhibitor of MGMT and ALDH significantly enhances the antitumor effect of alkylators as CP and TMZ in ER+ breast cancer.