Title

The beneficial effect of weight reduction on adverse cardiovascular outcomes following bariatric surgery is attenuated in patients with obstructive sleep apnea

Aurora Affiliations

Aurora Research Institute

Center for Integrative Research on Cardiovascular Aging

Aurora Cardiovascular Services

Bariatrics, S.C, Aurora Sinai Medical Center

Abstract

Weight loss after bariatric surgery is associated with reduction in adverse cardiovascular outcomes; however, the impact of obstructive sleep apnea (OSA) on reduction of cardiovascular outcomes after bariatric surgery in morbidly obese patients is not known. We retrospectively assessed differences in cardiovascular events after laparoscopic adjustable gastric banding (LAGB)-induced weight loss in patients with and without OSA before and after propensity score matching for age, sex, body mass index (BMI), and major comorbidities between the two groups and determined predictors of poor outcomes. OSA was present in 222 out of 830 patients (27%) who underwent LAGB between 2001 to 2011. Despite a similar reduction in BMI (20.0% and 20.8%), a significantly higher percentage of cardiovascular events were observed in patients with than without OSA (35.6% vs 6.9%; p

Document Type

Article

PubMed ID

29425382

DOI

10.1093/sleep/zsy028

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