Usefulness of atrial function for risk stratification in asymptomatic severe aortic stenosis

Aurora Affiliations

Aurora Cardiovascular Services, Aurora Sinai/Aurora St. Luke’s Medical Centers


AIM: We aimed to evaluate the usefulness of left atrial (LA) mechanics and stiffness over global left ventricular (LV) longitudinal strain (GLS) for risk stratification in severe aortic stenosis (AS).

METHODS: From a cohort of 89 prospective asymptomatic patients with severe AS and normal LV ejection fraction, 82 (32 men, mean age 73±10 years) truly asymptomatic patients, scheduled after a negative exercise echocardiogram, were enrolled. Forty age- and gender-matched prospective, asymptomatic subjects served as controls. Predefined end points were the occurrence of symptoms (dyspnea, angina, syncope), and death during follow-up.

RESULTS: At study entry, patients had: impaired LV GLS (p=0.001), reduced LA reservoir (p0.001), lower LA reservoir (p

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