Title

Clostridium difficile in inflammatory bowel disease: a retrospective study

Aurora Affiliations

Department of Gastroenterology, Aurora Healthcare

Abstract

Aim: To investigate the epidemiology and risk factors of

Methods: This is a retrospective study of patients diagnosed with IBD. 1006 charts were screened and 654 patients met the inclusion criteria. Patients were divided into 2 cohorts based on the presence of prior diagnosis of CDI. Statistical analysis with Pearson's chi-squared and two-sample

Results: The incidence of CDI among IBD patients was 6.7%. There was equal prevalence of CDI among Crohn's disease (CD) (

Conclusions: IBD patients are more susceptible to CDI at a younger age and often lack traditional risk factors. IBD patients with at least one CDI were more likely to require biologic therapy and had greater rates of extraintestinal manifestations.

Document Type

Article

PubMed ID

29109735

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