Article Title

The Burden of Hidradenitis Suppurativa in Maccabi Healthcare Services: Real-World Data Analysis

Publication Date



hidradenitis suppurativa, burden


Background/Aims: Hidradenitis suppurativa is a chronic, recurrent, inflammatory skin disease that presents with painful inflamed lesions in the apocrine gland-bearing areas of the body. Little is known on its medical and economic burden.

Methods: This retrospective cohort study was conducted in Maccabi Healthcare Services (MHS) using de-identified datasets. Included in this analysis were all MHS members with hidradenitis suppurativa diagnosed from Jan. 1, 2004, to Dec. 31, 2014. Data included sociodemographic details, chronic comorbid conditions and health care services utilization as well as prescriptions dispensed within 14 days after visits with hidradenitis suppurativa diagnosis.

Results: A total of 14,700 MHS members were detected to have at least one hidradenitis since 2004. Included in this study are 3,506 patients age 20 years and older with hidradenitis suppurativa (mean age: 38.5 ± 12.8; 63% female). Among study patients, 25.4% were obese, 24.7% suffered depression and 35.3% were treated with antidepressive therapy. In 2013, 39% and 29% of the patients visited a dermatologist and a surgeon, respectively. Medications frequently prescribed and purchased are topical antibiotics, topical steroids combined with antibiotics and systemic antibiotics minocycline. Medical procedures most common among study patients were wound treatment, incision and drainage, both during first year after index hidradenitis suppurativa diagnosis and annually.

Conclusion: The present study is one of the first to use real-world data on the burden of hidradenitis suppurativa. Results indicate that hidradenitis suppurativa is a relatively common inflammatory skin disease in Israel with a considerable medical and economic burden.




June 28th, 2016


August 12th, 2016